Lee County, Virginia is located in the Lenowisco Health District. It has 435.4 square miles of land area and is the 39th largest county in Virginia by total area. It is bordered by Wise and Scott County, Virginia, Hancock and Claiborne County, Tennessee, and Harlan and Bell County, Kentucky. There are 7 census tracts in the county. The county FIPS number is 51105.

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